Ambien (zolpidem) is hypnotic from the group imidazopyridines specific agonist omega-1-receptors of the CNS. Shortens the time to fall asleep, reduces the number of night awakenings, increases sleep duration and improves its quality. Extends phase II of sleep, phases of deep sleep (III and IV), does not affect the duration of REM sleep.
Typical Central muscle relaxant and anticonvulsant effects.
Sleep disorders: difficulty falling asleep, early night awakening.
Read the contraindications carefully before you decide to buy ambien online without prescription. Consult your doctor before use it. Contraindications include: severe respiratory insufficiency, sleep apnea, severe liver failure, childhood and adolescence to 15 years, I trimester of pregnancy, lactation (breastfeeding), hypersensitivity to zolpidem.
When administered to adults aged up to 65 years a single dose of 10 mg, if necessary, it may increase to 15-20 mg. For patients older than 65 years or with concomitant hepatic insufficiency initial single dose is 5 mg. Buy ambien online and take it just before bedtime. The course of treatment – from several days to 4 weeks.
- From the digestive system: in some cases abdominal pain, nausea, vomiting, diarrhea.
- CNS and peripheral nervous system: depending on dose and individual sensitivity (especially in elderly patients) – dizziness, impaired balance, ataxia, headache, daytime drowsiness, loss of attention, muscular weakness, diplopia, anterograde amnesia, paradoxical or mental reactions; when used in high doses or long-term treatment of possible rebound insomnia.
- Allergic reactions: skin rash, itching.
- Other: rare – violation of sexual desire, development of addiction, the formation of psychic and physical dependence (when used in a few weeks.
Zolpidem is contraindicated in pregnancy and lactation (breastfeeding).
Not recommended for use in infants.
Use with caution in patients with respiratory insufficiency. In case of liver failure, a dose reduction may be required.
If you cancel therapy of ambien online, the dose should be reduced gradually. The likelihood of drug addiction increases with prolonged use of zolpidem.
Not allow alcohol during the treatment period.
Effects on ability to drive vehicles and management mechanisms
During treatment should refrain from potentially hazardous activities, requiring concentration and high speed of psychomotor reactions.
With the simultaneous use of zolpidem with drugs that depress the central nervous system (including tranquilizers, barbiturates, antipsychotics, other hypnotics, antidepressants and antihistamines with sedative component, alcohol), mutual enhancement of effects is possible (caution is recommended, the dose of one or all drugs should be reduced ). The benzodiazepine-type anxiolytics increase the risk of drug dependence. When combined with imipramine, zolpidem reduces Cmax imipramine, possibly increased sleepiness and an increased incidence of anterograde amnesia, in combination with chlorpromazine, an extension of T1 / 2 of chlorpromazine is possible.
Symptoms: European post-marketing reports on zolpidem overdose report a violation of consciousness (from drowsiness to mild coma). Fixed one case of cardiovascular and respiratory disorders. There was a complete recovery after taking doses of zolpidem tartrate to 400 mg (40 times greater than MPDH).
Cases of overdose caused by the simultaneous administration of many drugs, depressing the central nervous system, including zolpidem, led to more severe consequences, up to lethal outcomes.
Treatment: induction of vomiting or immediate gastric lavage (depending on the condition), the purpose of activated charcoal. The monitoring of vital functions (breathing, pulse, blood pressure, etc.) is shown, if necessary, symptomatic and supportive therapy. It should be abandoned the use of any sedatives (even with pronounced stimulation). Hemodialysis is ineffective. A specific antidote is a benzodiazepine receptor antagonist flumazenil.