Ivermectin is an anthelmintic (anti-parasite) used to treat infections caused by certain parasites.
Moderate-certainty evidence finds that large reductions in COVID-19 deaths are possible using ivermectin.
Using ivermectin early in the clinical course may reduce numbers progressing to severe disease.
The apparent safety and low cost suggest that ivermectin is likely to have a significant impact on the SARS-CoV-2 pandemic globally.
Ivermectin is an FDA approved drug for use in humans to treat a variety of parasitic infections including parasitic worms, hookworm and whipworm.
It may also be used to treat other conditions and as a treatment of onchocerciasis, intestinal strongyloidiasis and onchocerciasis or river blindness.